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UHCW are working with colleagues in the UK and all around the world in the fight against COVID-19. Patients who have COVID may be invited to take part in these studies if they meet the inclusion criteria.

We are also taking part in a number of studies looking at the impact of COVID on patients and services at the Trust, which we may ask patients to participate in.

Patients are under no obligation to take part, and their standard care will not be affected if they decide not to take part.

Some of the studies we are currently conducting are below.


Prospective, Randomized, Parallel-Group, Open-Label Study to Evaluate the Efficacy and Safety of IMU-838, in Combination with Oseltamivir, in Adults with Coronavirus Disease 19

This trial aims to explore the effectiveness of a new drug taken orally, called IMU-838, in combination with Oseltamivir (Tamiflu) – one of the most widely used flu treatments in the UK – in patients with confirmed or suspected COVID-19.

Find out more here


Phase 3 multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of canakinumab on cytokine release syndrome in patients with COVID-19-induced pneumonia

This is a clinical trial looking at the effects of a medication called canakinumab on patients with COVID-19 pneumonia (an infection in one or both lungs). Patients who take part will be randomised to receive either canakinumab or placebo.

Find out more here


Coronavirus infection in primary or secondary immunosuppressed children

This study aims to monitor children and young people who have a condition or are taking medication that affects their immune system and makes them more vulnerable to infections during the coronavirus pandemic. Parents of immunosuppressed children, and the children and teenagers themselves, record their experiences of viral respiratory illnesses including COVID-19 on an online questionnaire.

Find out more here


Clinical Characterisation Protocol for Severe Emerging Infection

The purpose of the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) is to prevent illness and deaths from infectious disease outbreaks. This research aims to study COVID-19 to better understand its spread and behaviour. This will be done by collecting and analysing biological samples and data from patients with confirmed cases of the disease across the UK.

Find out more here


Pregnancy and Neonatal Outcomes in COVID-19

PAN COVID is a global registry of women with suspected or confirmed COVID-19 infection in pregnancy and their newborn babies.

Find out more here


Randomised evaluation of COVID-19 therapy

This national clinical trial aims to identify treatments that may be beneficial for people who have been admitted to hospital with suspected or confirmed COVID-19.

Find out more here


Maternal and perinatal outcomes of pandemic influenza or novel coronavirus in pregnancy

This study uses the UK Obstetric Surveillance System (UKOSS) to collect information about pregnant women who are admitted to hospital with confirmed COVID-19 infection, their health and the health of their baby or babies.

Find out more here