Coventry and Warwickshire Clinical Research Facility

The Coventry and Warwickshire Clinical Research Facility (CRF) receives funding from the National Institute of Health Research (NIHR) to provide the support and expertise required to conduct high quality experimental studies.

We offer dedicated facilities and support to researchers undertaking the following types of studies:

  • Early phase interventional studies (phase IIa and earlier)
  • Experimental medicine studies which are ‘nested’ within later phase studies and require specialised facilities, staff or equipment
  • High-intensity or high-complexity elements of later phase studies
  • Early stages of testing new techniques or new medical devices 

Based at University Hospitals Coventry and Warwickshire NHS Trust, the NIHR Coventry and Warwickshire CRF recruits from a socially and ethnically diverse patient population of over one million.

Research Facilities 

The NIHR Coventry and Warwickshire CRF benefits from access to a number of purpose-built research facilities at University Hospitals Coventry and Warwickshire NHS Trust.

Clinical Research Treatment Centre

The Clinical Research Treatment Centre is located in a purpose-built unit at University Hospital. The Centre includes a treatment area for outpatients or day patients comprising six treatment chairs, with the option of a bedded area. There is also a patient reception and waiting area, a separate clinical examination room, drug preparation and centrifuge room. The Clinical Research Treatment Centre staff are experienced in delivering treatments for research participants.

Patient Research Interface Suites

There are six Patient Research Interface (PRI) suites distributed throughout University Hospital, Coventry which are designed to provide researchers with dedicated research facilities near to, but independent from, the ward areas. Each suite includes two clinical examination rooms, two technical/equipment rooms, and one or two offices. The PRI suites provide an excellent environment for patients and volunteers to participate in clinical research studies in comfort and privacy.

Human Metabolism Research Unit (HMRU)

The Human Metabolism Research Unit (HMRU) is a custom-built facility designed to measure and analyse all facets of how an individual creates and uses energy. At the heart of the HMRU are two state-of-the-art whole body calorimeter rooms, which generate detailed 24-hour energy profiles for an individual. This unit is one of only two in the UK and the most advanced of its type in Europe.

The HMRU also contains a range of equipment for measuring anthropomorphic characteristics (e.g. height, weight, percentage body fat) including a BodPod for air displacement plethysmography, cardio-pulmonary exercise testing facilities and a vascular lab.

The HMRU is run by University Hospitals Coventry and Warwickshire NHS Trust in partnership with Warwick Medical School.

For more information visit https://www.mededcoventry.com/HMRU/.

Biomedical Research Unit (BRU) in Reproductive Health

Located in the Women’s Health department at University Hospital, Coventry the BRU in Reproductive Health provides the infrastructure and resources for conducting high quality clinical research in this patient population; including advanced ultrasound imaging and laboratory analyses. Women at risk of reproductive failure and obstetrical complications are seen in dedicated consultant-led research clinics before pregnancy. The BRU has been designed to be a welcoming and comfortable space for couples participating in studies.

Arden Tissue Bank

More information can be found here.

Our Research

The major focus of the NIHR Coventry and Warwickshire CRF is:

  • Metabolic medicine
  • Vascular medicine
  • Reproductive health
  • Cancer

These are complemented by additional areas of clinical research activity, including cardiology, gastroenterology and rheumatology / inflammation.

The CRF Team

The CRF team is led by Clinical Director, Professor Chris Imray, supported by CRF Delivery Manager, Tracy Gazeley, and CRF Senior Nurse, Julie Jones.  The CRF management team works closely with the Research and Development management team at University Hospitals Coventry and Warwickshire NHS Trust to ensure CRF activities are carried out to the highest possible standards and meet UK regulatory and governance requirements.

To contact the CRF please e-mail coventryandwarwickshirecrf@uhcw.nhs.uk.

Patients / Public:

Taking part in research

In the majority of research studies that take place in the NIHR Coventry and Warwickshire CRF, the participants are selected for the study by the researchers. If you are interested in taking part in a research study you could ask your Consultant at University Hospital Coventry and Warwickshire to consider any trials or other well-designed studies that you may be able to take part in.  You can also visit the UK Clinical Trials Gateway to find out about clinical trials running in the UK.

Get Involved!

The NIHR Coventry and Warwickshire CRF want to actively involve patients and members of the public in all stages of research. Find out more about how you can get involved here.

Find our 2017 – 2022 Patient and Public Involvement and Engagement strategy here.